GMP polyamine hybrid hydrogels: enhanced gel strength probed by z-spectroscopy

摘要

The self-assembling tendencies of guanosine-5'-monophosphate (GMP) can bedrastically increased using polyamines, with potential applications in the production ofbiocompatible smart materials, as well as for the design of anti-tumoral drugs based on G-quadruplex stabilization. Results from scanning electron microscopy (SEM), wide angle X-ray scattering (WAXS), rheology and nuclear magnetic resonance (NMR) zspectroscopy studies are presented.